Principal Investigator

Professor Tze Pin Ng 
National University of Singapore,
Yong Loo Lin School of Medicine,
Department of Psychological Medicine,
Level 9, NUHS Tower Block, 1E Kent Ridge Road, Singapore 119228

Data Contact

Dr. Gao Qi


Setting: South East and South West Region of Singapore
Start Date: 2003
End Date: Ongoing
Participants: 2804 (SLASI) and 2796 (SLASII) individuals aged 55+ years
Assessment Schedule: Baseline, follow-ups including 1-2 and 4 years

(1) Neuropsychiatric and neuropsychiatric assessments assessing dementia, MCI and cognitive decline; (2) Broad range of socioeconomic, psychosocial, behavioural, biological, clinical and nutritional factors; (3) Blood samples and genotyping; (4) Subgroups with structural and functional brain imaging. 

Further Information

  •  SLAS-I: Niti M, Yap KB, Kua EH, Tan CH, Ng TP. Physical, social and productive leisure activities, cognitive decline and interaction with APOE-epsilon4 genotype in Chinese older adults. Int Psychogeriatr. 2008 Jan 11:1-15.
  •  SLAS-II: Feng L, Chong MS, Lim WS, Lee TS,Collinson SL, Yap P, Ng TP. Metabolic syndrome (MetS) and amnestic mild cognitive impairment (aMCI): Singapore Longitudinal Ageing Studies-2 Findings. J Alzheimers Dis. 2013 Jan 1;34(3):649-57.