Participate in Research

Senior woman with laptop

By taking part in a CHeBA research study, you'll be partaking in world-leading research and making a valuable contribution to changing the future of dementia.


Maintaining Social Engagement study


Dr Suraj Samtani, a researcher at the Centre for Healthy Brain Ageing (CHeBA) is leading a team of researchers from UNSW Sydney, University of Queensland and Silverchain to find out how to help older adults maintain or enhance their social engagement and well-being. Silverchain is one of Australia’s largest aged care providers and provide services for over 21,000 older adults in the community. The project is funded by a Dementia Australia Research Foundation fellowship awarded to Dr Samtani. 
Dr Samtani’s goal is to help older adults with cognitive concerns feel more confident in social situations, feel connected and happier, and potentially improve their quality of life.

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Memory & Ageing Study 2

The original study, Sydney Memory and Ageing Study (MAS), ran for 14 years and is one of Australia’s largest and longest running studies of ageing and cognitive health. Over 200 publications using MAS data have appeared in a large range of respected national and international journals.

Following the success of MAS, MAS2 will recruit a new cohort that is a generation older. This new cohort will comprise Australians who have had different life experiences to the original MAS cohort.

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Developing Biomarkers for Vascular Cognitive Impairment (VCI)


This project aims to develop novel imaging biomarkers of early cerebrovascular alterations in VCI, and examine how they relate to brain vascular lesions, cognition (including dementia), blood biomarkers of vascular disease, and vascular risk factors. 

The VCI study is actively recruiting participants (aged 50-80 years old) who:

  • Have Vascular Dementia,
  • Have Vascular Mild Cognitive Impairment, or
  • Are healthy without cognitive impairment.

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Computerised Instrumental Activities of Daily Living Test (C-STAM)

The aim is to develop a computerised assessment tool to measure the ability to complete daily tasks such as shopping and finances. The tool will help clinicians identify early cognitive changes associated with dementia.

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Research in collaboration with: 



Healthy Body & Mind Program 


Are you aged 55 or over and living with osteoarthritis and cognitive decline?

In collaboration with the UNSW Lifestyle Clinic, we are looking for people over 55 with osteoarthritis and cognitive decline to take part in a 12-week physical and social activity and lifestyle education program.

Contact Dr Claire Burley at for further information or to register.


The MetMemory Study is a placebo-controlled study aiming to slow cognitive decline, using a safe medication used to treat diabetes and metabolic conditions.

Our aim is to slow loss of memory and other aspects of cognition with ageing, and examine whether metformin affects other aspects of metabolism, inflammation and the ageing process.

We're recruiting volunteers for a 3-year study.

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Research in collaboration with: 

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Join a Trial - MetMemory



AusCADASIL is a new study, recently established by researchers at CHeBA and collaborating institutes. This study investigates a genetic condition called CADASIL, which stands for Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy, often considered to be a 'pure' model for small vessel disease and vascular dementia. The study will include online and in-person assessments of clinical features, cognitive testing, brain MRI scan, ocular examination, and a blood sample for genetic and biomarker analysis. We will invite you to return for annual follow-up for four years, and we will ask you to involve a study partner who can answer some online questions about your health and wellbeing. 
We are looking for volunteers, aged 18 or over, for either the CADASIL cohort- including those with diagnosed CADASIL, CADASIL symptoms or a family history of CADASIL. We are also looking for healthy individuals without CADASIL to participate in this study. Family members may apply.

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