Cognitive Function & Ageing Studies

Principal Investigator

Carol Brayne
Cambridge Institute of Public Health
Forvie Site
Cambridge Biomedical Campus
Cambridge CB2 0SR

Data Contact

Linda Barnes


Setting: United Kingdom (Cambridge, Oxford, Newcastle, Nottingham, Gwynedd and Liverpool)
Start Date: 1989-1991
End Date:  
Participants: Over 18,000 individuals aged 65+ years
Assessment Schedule:  
Measures: (1) Cognitive function and dementia; (2) Broad range of sociodemographic, lifestyle and physical and mental health factors; (3) Functional limitations and social support; (4) Brain bank (in excess of 560 donated brains)

Further Information

  • Cognitive function and dementia in 6 areas of England and Wales: the distribution of MMSE and prevalence of GMS organicity level in the MRC CFA Study. The Medical Research Council Cognitive Function and Ageing Study (MRC CFAS) (1998). Psychological Medicine, 28, 319-35.
  • Matthews FE, Arthur A, Barnes LE, Bond J, Jagger C, Robinson L, Brayne C, on behalf of the Medical Research Council Cognitive Function and Ageing Collaboration (2013). A two-decade comparison of prevalence of dementia in individuals aged 65 years and older from three geographical areas of England: results of the Cognitive Function and Ageing Study I and II. Lancet, 382, 1405-12.