Principal Investigator
Hugh S. Markus
University of Cambridge
Summary
| Country | UK |
|---|---|
| Principal Investigator | Hugh S. Markus University of Cambridge |
| Key publication/reference | Pallucca C, Lisiecka-Ford DM, Wood L, Abul A, Jolly AA, Tozer DJ, Bell S, Forster A, Morris RG, Markus HS. Apathy After Stroke: Incidence, Symptom Trajectory, and Impact on Quality of Life and Disability. Neurology. 2024 Feb 13;102(3):e208052. doi: 10.1212/WNL.0000000000208052. Epub 2024 Jan 11. PMID: 38207223. |
| Years in which study conducted | 2017-2024 (completed) |
| Follow-up schedule | 30 days, 6 months, 12 months after stroke (1 year study) |
| Sample | |
| Sample size (baseline sample) | 200 |
| Population | Hospital (observational) |
| Age range | > 18 years old |
| Number of centres | 3 or more |
| Control group: number, population, selection | No |
| Assessment | |
| Stroke-related data | Yes |
| Functional tests | Yes |
| Neuropsychological/cognitive tests | MoCA (no detailed neuropsych tests) |
| Dementia diagnosis | Yes |
| MRI scans (type e.g., T1- weighted; when and how many) |
T1-weighted volumetric,T2-weighted,FLAIR,DWI |
| PET scans | No |
| Psychiatric exams | Apathy, depression, (no anxiety), Barthel index, no NPI Quality of life, mRS, activity scale |
| Genetics data (e.g., GWAS, APOE) | GWAS |
| Blood analysis | Cholesterol, glucose level |
