Stroke Registry Investigating cognitive Decline (STRIDE)

Principal Investigator

Vincent Mok
Division of Neurology,
Department of Medicine and Therapeutics,
Prince of Wales Hospital,
The Chinese University of Hong Kong,
Hong Kong Special Administrative Region, China.


Country Hong Kong
Principal Investigator Vincent Mok
Contact person (email)
Key publication/reference Yang, et al. Alzheimers Dement 2014
Years in which study conducted 2009-
Size 1013
Population: Hospital/community Hospital
Selection: consecutive/random Consecutive
Admit with previous stroke? Yes
Admit with TIA? Yes
Age range 20-98
Number of centres 1
Control group: number, population, selection None
Initial: Time and data collected/tests administered Med Hx, VRF, CT or MRI, lifestyle (physical and leisure activities, diet)
Detailed 3-6m: NΨ, depression, psychiatric disorders
Subsequent (follow-ups) Up to 5 years: gait speed, blood pressure
Stroke-related data NIHSS, TOAST
Functional tests/data None
Other medical tests/data Lifestyle (physical and leisurely activities, diet) 10m gait speed, homocysteine and bloods reserved for genetics testing in a subset of sample
Neuropsychological tests Subjective cognitive complaints, MMSE, MoCA
MRI scans, when and how many N=510 (T1, FLAIR)
PET scans 50 PiB (37 with incident dementia, 13 others)
Psychiatric exams/diagnoses Dementia, CDR, Geriatric Depression Scale, psychiatric disorders
Intervention trialled? No

CT=computed tomography scan, MedHx=medical history, VRF=vascular risk factors (hypertension, diabetes, atrial fibrillation, obesity, smoking etc.), NΨ=neuropsychological, TIA=transient ischemic attack, m=month, y=year