National Neuroscience Institute Study

Principal Investigator

Nagaendran Kandiah
Department of Neurology,
National Neuroscience Institute,
Duke-National University of Singapore Graduate Medical School,


Country Singapore
Principal Investigator Nagaendran Kandiah
Contact person (email)
Key publication/reference Kandiah et al. J Neurol Sci 2011; 309:92-95
Yatawara et al. Neurology 2018; 91:e45-e54
Kandiah et al. J Alzheimers Dis 2016; 49; 1169-77
Years in which study conducted 2011-2017
Size 506
Population: Hospital/community Hospital
Selection: consecutive/random Consecutive
Admit with previous stroke? No (?)
Admit with TIA? No (?)
Age range Mean=61
Number of centres 1
Control group: number, population, selection None
Initial: Time and data collected/tests administered MRI, VRF, cognitive symptoms, IQCODE
Detailed 3m: NΨ
Subsequent (follow-ups) 6m:
1y (up to 5y): NΨ
Stroke-related data ?
Functional tests/data Rankin
Other medical tests/data None
Neuropsychological tests MMSE, MoCA, Frontal Assessment Battery
MRI scans, when and how many Initial (n=506), WMHs
PET scans No
Psychiatric exams/diagnoses Post stroke cognitive impairment, Dementia, CDR, depression (PHQ9)
Intervention trialled? No

CT=computed tomography scan, MedHx=medical history, VRF=vascular risk factors (hypertension, diabetes, atrial fibrillation, obesity, smoking etc.), NΨ=neuropsychological, TIA=transient ischemic attack, m=month, y=year