Maastricht Cognitive Disorders After Stroke (CODAS)

Principal Investigators

Frans Verhey, Jan Lodder
Contact: Seb Köhler
School for Mental Health and Neuroscience,
Department of Psychiatry and Neuropsychology,
Maastricht University,
The Netherlands.


Country Netherlands
Principal Investigators Frans Verhey, Jan Lodder
Contact person (email) Seb Köhler (
Key publication/reference Rasquin et al. Neuroepidemiol 2005;24:189–195
Years in which study conducted 2000-2001 (baseline)
Size 194 (of which 18 haemorrhagic stroke)
Population: Hospital/community


Selection: consecutive/random


Admit with previous stroke? No
Admit with TIA? Yes
Age range 40+
Number of centres 1 (University Hospital Maastricht)
Control group: number, population, selection Maastricht Aging Study (n=750), population-based
Initial: Time and data collected/tests administered Within 48 hours: CT, MMSE, MedHx
Detailed 1m: NΨ
Subsequent (follow-ups) 6m, 12m, 24m: NΨ
Stroke-related data CT-related information
Functional tests/data ADLs (Interview for Deterioration in Daily living activities in Dementia), Rankin scale
Other medical tests/data VRF; APOE and ACE-I/D genotyping
Neuropsychological tests Test battery, CAMCOG, MMSE
MRI scans, when and how many No
PET scans No
Psychiatric exams/diagnoses Dementia (NINDS-AIREN, ADDTC), vMCI
Intervention trialled? No

CT=computed tomography scan, MedHx=medical history, VRF=vascular risk factors (hypertension, diabetes, atrial fibrillation, obesity, smoking etc.), NΨ=neuropsychological, TIA=transient ischemic attack, m=month, y=year