Epidemiologic Study of the Risk of Dementia After Stroke

Principal Investigator

David Desmond


Country USA
Principal Investigator David Desmond
Contact person (email) dwdesmond@gmail.com
Key publication/reference Desmond et al. Neurology 2000;54:1124-1131
Desmond et al. Stroke 2002;33:2254-2262
Years in which study conducted 1988-1999
Size 585
Population: Hospital/community Hospital
Selection: consecutive/random Consecutive
Admit with previous stroke? Yes
Admit with TIA? No
Age range 60+
Number of centres 1
Control group: number, population, selection N=249 Random selection from surrounding community; spouses of patients; neighbourhood volunteers
Initial: Time and data collected/tests administered Within 7-10 days: MedHx, VRF, function, depression, MMSE, neurologic exam
Detailed 3m: extended NΨ, function, depression, MMSE, neurologic exam
Subsequent (follow-ups) Annually (as per 3m)
Stroke-related data Stroke Data Bank Stroke Severity Scale
Functional tests/data Barthel Index, Blessed Functional Activity Scale
Other medical tests/data None
Neuropsychological tests Test battery
MRI scans, when and how many No
PET scans No
Psychiatric exams/diagnoses Dementia, depression (Hamilton Depression Rating Scale)
Intervention trialled? No

CT=computed tomography scan, MedHx=medical history, VRF=vascular risk factors (hypertension, diabetes, atrial fibrillation, obesity, smoking etc.), NΨ=neuropsychological, TIA=transient ischemic attack, m=month, y=year