Action on Secondary Prevention Interventions and Rehabilitation in Stroke Study (ASPIRE-S)

Principal Investigator

Lisa Mellon
RCSI Psychology
Royal College of Surgeons in Ireland
Lower Mercer Street
Dublin, Ireland.


Country Ireland
Principal Investigator Lisa Mellon
Contact person (email) Lisa Mellon (
Key publication/reference Mellon et al. BMC Neurology 2015; 15: 31
Years in which study conducted 2011-2012
Size 256
Population: Hospital/community Hospital
Selection: consecutive/random Consecutive
Admit with previous stroke or TIA Yes
Admit with TIA? No
Age range 69±12.9 (IQR 61-78)
Number of centres 3
Control group: number, population, selection None
Initial: Time and data collected/tests administered 72 hours: function, stroke severity, VRF
Detailed As per 6 mo follow-up
Subsequent (follow-ups) 6 mo: cognitive, function, psychiatric, blood analysis
Stroke-related data Scandinavian Stroke Scale, Bamford classification, TOAST
Functional tests/data Modified Rankin Scale
Other medical tests/data Blood pressure, blood analysis
Neuropsychological tests MoCA
MRI scans, when and how many No
PET scans No
Psychiatric exams/diagnoses Mood disorder (Hospital Anxiety and Depression Scale)
Intervention trialled? No

CT=computed tomography scan, MedHx=medical history, VRF=vascular risk factors (hypertension, diabetes, atrial fibrillation, obesity, smoking etc.), NΨ=neuropsychological, TIA=transient ischemic attack, m=month, y=year