Senior man

The MetMemory Study is a placebo-controlled study aiming to slow cognitive decline, using a safe medication used to treat diabetes and metabolic conditions.

This research collaboration between CHeBA and the Garvan Institute, funded by the National Health and Medical Research Council, is recruiting volunteers for a 3-year study examining the effects of metformin on cognition, brain anatomy and early signs of dementia.

By registering to participate in this study you may be able to help us achieve our objective: to slow loss of memory and other aspects of cognition with ageing, and examine whether metformin affects other aspects of metabolism, inflammation and the ageing process. 

Metformin is a safe medication used to treat diabetes, but also other metabolic/hormonal conditions.

We’re looking for people who meet the following eligibility criteria:

  • Live in the greater Sydney region; 
  • Are over 60 years of age;
  • Are slightly overweight but do not have diabetes;
  • Do not have dementia;
  • Have concerns about changes in memory or thinking;
  • Are not currently taking metformin.

This research is led by Professor Katherine Samaras, Clinical Fellow at the Garvan Institute.

For more information and to register your interest call (02) 9295 8585 or email

Research in collaboration with:

Garvan Institute Logo
This study has been approved by the St Vincent’s Hospital Human Research Ethics Committee (HREC 2020 / 01652)