The Organisation of the Elderly Connectome

CHeBA Research Project: The Organisation of the Elderly Connectome
The scans of community-dwelling participants aged 70-90 years are studied in order to examine normal age-related changes in the structural organisation of the elderly brain.

Description

Prior investigations of human brain structural networks have primarily focused on healthy young adults and clinical samples. We study the scans of community-dwelling participants aged 70-90 years in order to examine normal age-related changes in the structural organisation of the elderly brain.

organisation-of-the-elderly-connectome-diagram.jpg

Aims

  • To examine age-related changes in structural topological organisation of the elderly brain.
  • To investigate whether both hemispheric asymmetry and sex differences in structural networks are present in an older population.
  • To examine changes in the structural network using functional network measures.

Findings

Findings from this study were published in the journal, Neuroimage. The connectivity data of all cognitively healthy elderly subjects were collected as part of the Sydney Memory and Ageing Study and analysed by Perry et al (http://dx.doi.org/10.1016/j.neuroimage.2015.04.009).