PROPOLIS

Principal Investigator

Aleksandra Klimkowicz-Mrowiec
Department of Neurology,
Jagiellonian University Medical College,
Botaniczna 3, 31-503,
Krakow, Poland.
Aleksandra.Klimkowicz@mp.pl

Summary

Study Name PROPOLIS
Country Poland
Principal Investigator Aleksandra Klimkowicz-Mrowiec
Contact person (email) Aleksandra.Klimkowicz@mp.pl
Key publication/reference

Pasińska P, Wilk A, Kowalska K, et al. The long-term prognosis of patients with delirium in the acute phase of stroke: PRospective Observational POLIsh Study (PROPOLIS). 
 J Neurol. 2019;266(11):2710-2717.

Years in which study conducted 2014-2016 recruitment
Follow-up ongoing (5 y)
Sample  
Size 750
Population: Hospital/community Hospital
Selection: consecutive/random Consecutive
Admit with previous stroke? Yes
Admit with TIA? Yes
Age range +40
Number of centres 1
Control group: number, population, selection No
Assessment  
Initial assessment (when and what    
     were the assessments?)
Within first week medical history, The Cumulative Illness Rating Scale (CIRS) , function, Montreal Cognitive Assessment (MoCA), Frontal Assessment Battery] Cognitive Test for Delirium between day1-2 and on the 7th day after admission.  ct/mri
First detailed assessment 3 m, neuropsychology, neuropsychiatry, IQCODE, mRS
Follow-ups 12m, 5 y
Stroke-related data  
Functional tests/data mRS, IADL
Other medical tests/data (e.g. APOE?)  
Neuropsychological tests Test battery
MRI scans (when, how many and what type) During hospital stay-in some patients
PET scans /no
Psychiatric exams Patient Health Questionnaire (PHQ–9), State Trait Anxiety Inventory (STAI) , Apathy Evaluation Scale-C (AES-C), Buss-Durkee Hostility Inventory (BDHI)
Dementia diagnosis criteria DSM-5
Intervention trialled? No

CT=computed tomography scan, MedHx=medical history, VRF=vascular risk factors (hypertension, diabetes, atrial fibrillation, obesity, smoking etc.), NΨ=neuropsychological, TIA=transient ischemic attack, m=month, y=year