Morphology of Cortical Surface: Cortical Folding Pattern and Sulcal Width

CHeBA Research Project: Morphology of Cortical Surface: Cortical Folding Pattern and Sulcal Width
The cortical folding process begins very early, starting from 10 weeks of foetal life. Therefore, alterations in cortical development can provide us with important clues about the resulting morphology.

Description

The cortical folding process begins very early, starting from 10 weeks of foetal life. Therefore, alterations in cortical development can provide us with important clues about the resulting morphology. Such morphological changes in the brain are associated with ageing, and this is possibly related to the thinning of the gyri, due to reduction in gyral grey matter and white mat­ter. Sulcal widening is commonly used by radiologists as a measure of cortical atrophy in the clinical setting.

Project Members