Inflammatory Markers and Brain Structure

image - Neuroinflammation 0
Project Main Description: 

Using circulating inflammatory markers and magnetic resonance imaging (MRI), recent studies have associated inflammation with brain volumetric measures. We investigate the relationship between a novel inflammatory biomarker and grey matter volumes in the brain, which may help in the early diagnosis of pathological brain ageing.


To examine the relationship of serum levels of a divergent transforming growth factor – beta (TGF-β) superfamily cytokine, Macrophage Inhibitory Cytokine – 1 (MIC-1/GDF15), with human brain grey matter (GM) volumes, in a community-dwelling sample aged 70-90 years over two years.

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