Brain Stimulation and Cognitive Training

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Project Main Description: 

Recent brain stimulation research suggests that mild brain stimulation (ie. tDCS) when given during performance of a cognitive (memory) task in a single session improves performance.  Also patients who have had a stroke learn how to do certain 'hands-on' tasks better when participants receive a course of brain stimulation treatment.  There is research that computerised brain training benefits people with memory problems (ie. MCI or Mild Cognitive Impairment).  People with aMCI experience mild difficulties with their memory but are otherwise functioning well in their day to day activities.  Usually the individual notices that their memory has recently got worse compared to a few years ago.  They may experience more difficulty remembering names, appointments or where they put something.  People with aMCI are at increased risk of future dementia.


This study aims to directly investigate whether computer brain training when combined with mild brain stimulation is better than computer brain training alone, in improving memory and thinking in patients with amnestic mild cognitive impairment (aMCI).

Design and Method: 

Assessments conducted at baseline, post CFCT, and at 3 months follow-up will examine whether CFCT combined with tDCS produces greater cognitive and functional gains than CFCT alone and whether these gains are maintained over time. Participants also undergo MRI brain scans at baseline and after completing their treatments.

For more information, please call Dr Adith Mohan or Dr Donel Martin on (02) 9382 8353 or email or

Study Investigators

Dr Adith Mohan is a neuropsychiatrist based at the Prince of Wales hospital, where he has a clinical role, including work with patients with memory disorders. His research interests include the areas of brain stimulation therapies for psychiatric and movement disorders.

Dr Donel Martin is a clinical neuropsychologist and post doctoral researcher based at the Black Dog Institute. His research interests include investigating novel treatments for psychiatric disorders, including novel brain stimulation techniques (eg. transcranial direct current stimulation (tDCS), and using brain stimulation to enhance cognitive functioning.

Project Status: 
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