image - Morphology Of Cortical Surface
Status: Current

The cortical folding process begins very early, starting from 10 weeks of foetal life. Therefore, alterations in cortical development can provide us with important clues about the resulting morphology. Such morphological changes in the brain are associated with ageing, and this is possibly...

image - Structural Brain Networks
Status: Current

Traditionally, the study of the relationship between brain structure, brain ageing and associated neuropsychiatric disorders involved examining circumscribed atrophy or other abnormalities of various grey or white matter regions of interest by using 3D T1- weighted structural MRI scans. However...

image - Normative Study 1
Status: Current

Many cognitive abilities ‘naturally’ decline as we get older. The prevalence of Alzheimer’s and other dementias also increases with older age. Therefore, distinguishing dementia and milder neurocognitive impairments from normal age‐related cognitive change is a major challenge for clinicians and...

image - PiB PET In Twins Study%281%29
Status: Current

One hallmark of Alzheimer’s disease (AD) is a build up of plaques in the brain, starting years before symptoms are observed. We use PiB-PET brain scans to determine the degree of plaque build-up in pairs of twins at risk of developing AD, and calculate the heritability of these plaques. We will...

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