Status: Current

Diagnosis of mild dementia and Mild Cognitive Impairment (MCI) is challenging because cognitive problems are subtle and difficult to detect. Therefore, diagnosis is commonly delayed and many older adults will not receive a diagnosis at all. Our study will evaluate the potential of a brief,...

image - Brain And Genetics
Status: Current

In order to better understand the pathways associated with normal and pathological brain ageing, we are studying the genetic contributions to cortical and sub-cortical brain structures. Prior research suggests brain structures have moderate to strong heritability.However, few studies have...

Picture of hands
Status: Current

The relationship between inflammation and geriatric depression is well-established, and offers the potential for the development of novel therapeutic strategies based on inflammatory targets. However, the relationship between depression and inflammation is complicated by age-associated factors (...

image - Capacity Building Resized2
Status: Current

CHeBA’s Capacity Building Grant (CBG) is an NHMRC-funded project which aims to develop the careers of future research leaders for the prevention and management of mental disorders in older Australians, particularly age-related brain diseases such as Alzheimer’s disease and other dementias. With...

image - Karen Berman Trial 0
Status: Current

A multinational, multicentre, randomised, double-blind, parallel-group, placebo-controlled study of the effect on cognitive performance, safety, and tolerability of SAR110894D at the doses of 0.5 mg, 2 mg, and 5 mg/day for 24 weeks in patients with mild to moderate Alzheimer's...

image - OATAS3
Tags: OATS; twins; twin study Status: Current

The Older Australian Twins Study is a longitudinal, multi-centre study that investigates healthy brain ageing in older twins (65+ years). Healthy ageing is characterised by low levels of disability, high cognitive and functional capacity, and an active engagement in life. The most important...

image - 7   SCS Photo Colour   Margaret Sommerville 99 Years Old And Major Cyril Bunny 98 Years Old
Status: Current

The age composition of Australia’s population is projected to change considerably over the coming decades, with elderly Australians the fastest growing proportion of the population. This is particularly true of the centenarians, the exceptional group of individuals who reach...

image - DSC 0045 0
Status: Current

The Sydney Memory and Ageing Study (Sydney MAS) began in 2005 to examine the clinical characteristics and prevalence of mild cognitive impairment (MCI) and related syndromes, and to determine the rate of change in cognitive function over time.  It is one of the largest...

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