image - MiRNA Cloud
Tags: miRNA, microRNA, Blood biomarkers, Alzheimer's Disease, dementia, diagnosis Status: Current

One of the barriers to the development of effective therapy for Alzheimer's disease (AD) is the lack of a specific biomarker that allows identification of the disease prior to the onset of clinically apparent cognitive impairment when the underlying brain pathology is already advanced and damage...

image - Proteomics Compressed
Tags: Proteomics, Alzheimer's Disease, Apolipoproteins Status: Current

Blood is not only a repository for a variety of disease biomarkers, but its constituents can also reflect the status of the body as it ages, responds to lifestyle and environmental impacts such as nutrition, exercise and education, and reflects changes within the body such as response to disease...

image - Wethinkyoucandance
Status: Current

People with dementia living in residential aged care have low levels of physical activity and exercise programs tend to be poorly attended. We think you can dance! is a cognitively enriched social dance...

image - Jaemin
Status: Current

Proteomics is the large scale study of the protein complement of a living organism. Proteins are involved in a range of cellular processes, including ageing. We hope to better understand this role by studying protein expression, function and changes in normal ageing and age-related disorders,...

image - MRI CHeBA
Status: Current

Ageing affects the functional networks of the brain, impacting cognition, sensory and motor skills. Resting-state functional connectivity is a basic measure of the brain’s functional network. Previous studies have extracted resting-state functional connectivity measures from prior defined...

image - Sto
Status: Current

Prior investigations of human brain structural networks have primarily focused on healthy young adults and clinical samples. We study the scans of community-dwelling participants aged 70-90 years in order to examine normal age-related changes in the structural organisation of the elderly brain...

image - Brain Scan
Status: Current

Biomarkers (short for biological markers) are substances which can be objectively measured and evaluated as an indicator of risk or progression of a disease. White matter loss is a common finding in Alzheimer’s disease (AD), but the mechanisms are not well understood. We investigate white matter...

image - Neuroinflammation 0
Status: Current

Using circulating inflammatory markers and magnetic resonance imaging (MRI), recent studies have associated inflammation with brain volumetric measures. We investigate the relationship between a novel inflammatory biomarker and grey matter volumes in the brain, which may help in the early...

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