My main research focus is to gain a better understanding of the genetic and environmental factors involved in ageing, longevity and age-related disease, including dementia. The genetic factors that may be involved include variation at the nucleotide level, epigenetic variation, epistasis and gene-environmental interactions. Current research is being undertaken using large population cohorts of older Australians and examining the genetic variation and environmental factors associated with ageing phenotypes. The establishment of collaborations with national and international investigators and consortia is enabling investigation of these age-related questions on a larger scale.
Broad Research Areas:
Human Ageing, Genetics - Genome Analysis, Epigenomics, Transcriptomics, Gerontology - Geriatrics, Epidemiology, Psychiatry
Society Memberships & Professional Activities:
American Human Society of Genetics, International Society to Advance Alzheimer Research and Treatment (ISTAART), Australasian Society for Psychiatric Research (ASPR) , Participant in the CSIRO Scientists in Schools Program
Specific Research Keywords:
Genetics, Genomics, Ageing, Biomarker, Dementia, Epigenetics, Transcriptomics, Mental Health