Principal Investigator
Dr Gary Kui Kai Lau
Division of Neurology, Department of Medicine
Queen Mary Hospital, Hong Kong
gkklau@hku.hk
Summary
| Country | Hong Kong |
|---|---|
| Principal Investigator | Dr Gary Kui Kai Lau |
| Contact person (email) | gkklau@hku.hk |
| Key publication/reference | Lau et al. Total small vessel disease score and risk of recurrent stroke: validation in 2 large cohorts. Neurology 2017 Jun 13;88(24):2260-2267. |
| Years in which study conducted | Since 2008 |
| Sample | |
| Size | ~1000 subjects from 2008-2015 with baseline and follow-up assessments, all with MRI with markers of SVD characterised |
| Population: | Hospital |
| Selection: | Consecutive |
| Admit with previous stroke? | Yes |
| Admit with TIA? | Yes |
| Age range (minimum - maximum, or inclusion criteria e.g. 40+) | 18+ |
| Number of centres | 1 |
| Control group: number, population, selection | - |
| Assessment | |
| Initial: Time and data collected/tests administered | Baseline medical data |
| First detailed assessment | 2008 |
| Follow-ups | Every 3-6 months according to clinical need ~3-4 year follow-up data available for cohort from 2008-2015 |
| Stroke-related data | - |
| Functional tests/data | mRS at 1 year after stroke onset for cohort from 2008-2015 |
| Other medical tests/data | Blood tests |
| Neuropsychological tests | Serial MOCA and cognitive assessments included since 2018 |
| MRI scans, when and how many | 2008 – 2015: ~1000 MRI scans analysed in detail |
| PET scans | No |
| Psychiatric exams | Pending |
| Dementia diagnosis criteria | VASCOG |
| Intervention trialled? | No |
