Principal Investigator
Pr Olivier Godefroy
Service de Neurologie
CHU Amiens
80054 Amiens Cedex
France.
Godefroy.Olivier@chu-amiens.fr
Summary
Country | France |
---|---|
Principal Investigator | Prof. Olivier Godefroy |
Contact person (email) | godefroy.olivier@chu-amiens.fr |
Key publication/reference | Godefroy O, et al. Int J Stroke. 2012; 7:362-3. |
Years in which study conducted | 2010-5 (AV45 PET substudy on-going) |
Sample | |
Size | 360 |
Population: Hospital/community | Hospital |
Selection: consecutive/random | Consecutive |
Admit with previous stroke? | Yes |
Admit with TIA? | No |
Age range | 40-80 |
Number of centres | 4 |
Control group: number, population, selection | French healthy controls (n=1003) |
Assessment | < |
Initial: Time and data collected/tests administered | MedHx, VRF, clinical, stroke characteristics, IQCODE, MMSE-MoCA, |
Detailed | 6m:clinical, NΨ,psychiatric |
Subsequent (follow-ups) | 1/yrs according to status |
Stroke-related data | NIHSS, ASCO, MRI |
Functional tests/data | Rankin, Barthel, IADL, DAD (subsample) |
Other medical tests/data | HMPAo SPECT or/and CSF biomarkers when clinically indicated |
Neuropsychological tests | French adaptation of Harmonization SP |
MRI scans, when and how many | MRI at 6m (and if possible initially) |
PET scans | AV45 PET in CI subsample (planned: n=100) |
Psychiatric exams/diagnoses | Depression (CESDS); anxiety (Goldberg); NPI; Dysexecutive Behavior (Behavioral Dysexecutive Syndrome Inventory) Dementia (DSM-V), VaD, VCI, |
Intervention trialled? | No |
CT=computed tomography scan, MedHx=medical history, VRF=vascular risk factors (hypertension, diabetes, atrial fibrillation, obesity, smoking etc.), NΨ=neuropsychological, TIA=transient ischemic attack, m=month, y=year