Cognitive Function After Stroke (CogFAST)

Principal Investigator

Rajesh  Kalaria
Institute for Ageing and Health,
Newcastle University,
Campus for Ageing & Vitality,
Newcastle upon Tyne NE4 5PL, UK.
r.n.kalaria@ncl.ac.uk

Summary

Country UK
Principal Investigator Raj Kalaria
Contact person (email) Raj.kalaria@ncl.ac.uk
Key publication/reference Allan et al. Brain 2011:134:3713-3724
Years in which study conducted 2002-2012
Sample  
Size 115
Population: Hospital/community Hospital
Selection: consecutive/random Stroke registries
Admit with previous stroke? Yes
Admit with TIA? ?
Age range 75+
Number of centres Multiple
Control group: number, population, selection None
Assessment  
Initial: Time and data collected/tests administered Not until 3m after stroke.
Detailed 3m: MedHx, neurological deficits, blood tests, CT, NΨ
Subsequent (follow-ups) 15m: repeat of 3m; NΨ: 1-8y (annually)
Stroke-related data Oxford Community Stroke Project Classification
Functional tests/data ?
Other medical tests/data APOE genoytping
Neuropsychological tests CAMCOG, Cognitive Drug Research computerized battery, MMSE, etc.
MRI scans, when and how many 3m (n=110); 2y (n=50)
PET scans No
Psychiatric exams/diagnoses Dementia, depression (Cornell Depression Scale)
Intervention trialled? No

CT=computed tomography scan, MedHx=medical history, VRF=vascular risk factors (hypertension, diabetes, atrial fibrillation, obesity, smoking etc.), NΨ=neuropsychological, TIA=transient ischemic attack, m=month, y=year