Principal Investigator
Regis Bordet
Department of Pharmacology,
University of Lille,
INSERM
U1171, 59045 Lille, France.
Regis.bordet@univ-lille2.fr
Summary
| Country | France |
|---|---|
| Principal Investigator | Régis Bordet |
| Contact person (email) | regis.bordet@univ-lille2.fr |
| Key publication/reference | Clinicaltrial.gov: NCT01330160 |
| Years in which study conducted | 2011- |
| Sample | |
| Size | 195 |
| Population: Hospital/community | Hospital |
| Selection: consecutive/random | Consecutive |
| Admit with previous stroke? | Yes |
| Admit with TIA? | Yes |
| Age range | >40 years |
| Number of centres | 2 (Lille, Rouen) + link to German centers through DEMDAS study |
| Control group: number, population, selection | No |
| Assessment | |
| Initial: Time and data collected/tests administered | Within 72 hours: MedHx, VRF, MRI, blood analyses, MoCa, MMSE, IQCODE |
| Detailed | (initial) |
| Subsequent (follow-ups) | 6m, 12m, 36m, 60m: NΨ, biological samples, MRI |
| Stroke-related data | NIHSS, TOAST, ASCOD |
| Functional tests/data | Modified Rankin Scale, Barthel Index |
| Other medical tests/data | Plasma biomarkers (vascular, inflammation, trophic factors, AD markers); DNA |
| Neuropsychological tests | Test battery
MoCA |
| MRI scans, when and how many | MRI initial, 6m, 36m ,60m |
| PET scans | At 12m (small number of selected patients) |
| Psychiatric exams/diagnoses | Dementia, CDR, depression (CES-D), apathy (Lille Apathy Rating Scale), anxiety (Hamilton Anxiety Scale) |
| Intervention trialled? | No |
CT=computed tomography scan, MedHx=medical history, VRF=vascular risk factors (hypertension, diabetes, atrial fibrillation, obesity, smoking etc.), NΨ=neuropsychological, TIA=transient ischemic attack, m=month, y=year
