World-First Memory Trial

Are you concerned about your memory?

To participate in this trial please contact (02) 9382 8353.

There is increasing concern regarding the lack of effective interventions for people who are at risk for dementia.

Medication treatments so far have shown minimal effects for assisting memory.

Our research team, funded by CHeBA and Alzheimer's Australia, has been conducting a world-first clinical trial investigating a new approach for improving memory.  This involves combining brain training exercises with a non-invasive mild form of brain stimulation. The idea is that by adding the mild brain stimulation, this will "boost" the effects of the brain training, by enhancing the brain's neuroplasticity. 

The trial so far has shown promising results, with some participants showing memory improvements.  We are currently recruiting participants aged 60 to 85 with mild memory problems for the last phase of the study, which includes a brain imaging component to help understand what brain changes are associated with memory improvements.

Who is eligible to participate?

You may be eligible to participate if you are:

  • Concerned about your memory
  • Aged between 60 and 85 years

What is expected?

You will be expected to answer some questions about your health and memory, and attend the Black Dog Institute in Randwick.  Each session involves computer brain training with or without mild brain stimulation and lasts approximately 45 minutes. 

Will I benefit from the study?

There is some indication that computerised brain training may be effective in improving memory in people with aMCI.  So it is possible that you will have some benefit whether or not you are in the group that will get mild brain stimulation.

What happens with the results?

The overall results after analysis will be disclosed to the the ethics committee for ongoing monitoring, published in scientific journals and presented at conferences and other professional forums.  In any publication, information will be provided in such a way that you cannot be identified.

What is aMCI?

People with aMCI experience mild difficulties with their memory but are otherwise functioning well in their day to day activities.  Usually the individual notices that their memory has recently become worse compared to a few years ago.  They may experience more difficulty remembering names, appointments or where they put something.  People with aMCI are at increased risk of future dementia.

PHONE (02) 9382 8353

For more information, please call Dr Adith Mohan or Dr Donel Martin on (02) 9382 8353 or email or

Study Investigators

Dr Adith Mohan is a neuropsychiatrist based at CHeBA where he has a research role and at the Prince of Wales hospital, where he has a clinical role, including work with patients with memory disorders.  His research interests include the areas of brain stimulation therapies for psychiatric and movement disorders.

Dr Donel Martin is a clinical neuropsychologist and post doctoral researcher based at the Black Dog Institute.  His research interests include investigating novel treatments for psychiatric disorders, including novel brain stimulation techniques (eg. transcranial direct current stimulation (tDCS), and using brain stimulation to enhance cognitive functioning.


image - TDCS And Cognitive Training Small
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