Systems of Care in Minor Stroke & TIA: Cognition (INSIST-COG)

Principal Investigator

Frini Karayanidis
Behavioural Sciences Building
University Drive
Callaghan, NSW 2308


Country Australia
Principal Investigator Frini Karayanidis
Contact person (email)
Key publication/reference  
Years in which study conducted Recruitment 2017-2018
Follow-up (funding dependent) 2019-2020
Size Target numbers: 120
Population: Hospital/community Community
Selection: consecutive/random Consecutive
Admit with previous stroke? Yes
Admit with TIA? Yes
Age range 40-90yrs
Number of centres 1
Control group: number, population, selection 50, healthy ageing, HMRI Volunteer Register
Initial: (when and what were the assessments?) Post event: MedHX, VRF, CT 78%, MRI 39%
First detailed assessment 1-5y: NΨ, MRI, EEG, physiological, psychiatric
Follow-ups Follow-up (funding dependent) 2019-2020
Stroke-related data MRI
Functional tests/data EEG during cognitive control tasks and at rest
Other medical tests/data BP, BMI, WHR
Neuropsychological tests NIH toolbox cognitive battery, TMT, MoCA
MRI scans, when and how many 2017 (1-5y post event): 43 T1, FLAIR and DWI
PET scans No
Psychiatric exams/diagnoses Depression and anxiety (HADS), quality of life (EQ-5D-3L)
Dementia diagnosis criteria MoCA <19
Intervention trialled? No

CT=computed tomography scan, MRI= magnetic resonance imaging, EEG= electroencephalogram, BP= blood pressure, BMI= body mass index, WHR = waist to hip ratio, TMT= trail making test, MoCA= Montreal Cognitive Assessment, HADS= hospital anxiety and depression scale, EQ-5D-3L= European quality of life scale, MedHx=medical history, VRF=vascular risk factors (hypertension, diabetes, atrial fibrillation, obesity, smoking etc.), NΨ=neuropsychological, TIA=transient ischemic attack, m=month, y=year