Blog: The Brain Dialogues, filtered by tag: Longitudinal studies

11 Dec 2017

Findings from the Older Australian Twins Study

Pictured Left to Right: Suzy Forrester (OATS Administrative Assistant) & Vibeke Catts (OATS Study Coordinator)
Suzy Forrester (OATS Administrative Assistant) & Vibeke Catts (OATS Study Coordinator)
HEIDI DOUGLASS | h.douglass@unsw.edu.au Established by CHeBA staff in 2007, the Older Australian Twin Study (OATS) is the largest and longest running Australian research study of its kind investigating healthy brain ageing. By studying older twins (aged 65+ years) over time, OATS allows researchers to investigate the complex interactions between multiple genetic and environmental factors which cause brain diseases. Over the last decade, OATS has generated over 32 published papers and contributed to 8 international consortia, providing valuable insights into healthy brain ageing and age-… Read More

Exploiting Big Data for Dementia Research

PROFESSOR PERMINDER SACHDEV This article was first published in InformAge, Volume 2, Issue IV December 2015 (Summer). Dementia is a global problem, and there is a worldwide effort to identify risk and protective factors, determine early biomarkers, and develop novel treatments for dementia. A survey of the international research scene reveals that many groups are working in relative isolation on projects that are similar to research conducted elsewhere. Very often, the individual projects are not large enough to provide conclusive answers to complex research questions. A recent… Read More
12 May 2015

Doubling the Data Through Twins Research

KATE CROSBIE and HEIDI DOUGLASS | h.douglass@unsw.edu.au For John Stapleton, the best thing about being a twin was never being bullied at school: “There were always two of us to fight”. For Terry Stapleton, it’s the “stronger bond” between twins; that, and meeting John for a beer most Fridays at The Oaks in Neutral Bay. Both twins maintain a physically and mentally active life, but in different ways. These differences, as well as their similarities, are helping CHeBA researchers understand the role of genetic and environmental factors in cognition and healthy ageing. John and Terry… Read More

Living to 100

CHeBA Blog: Living to 100
Pictured L-R: Professor Robyn Richmond, Major Cyril Bunny (at 98 years old), Professor Perminder Sachdev AM, Margaret Sommerville (at 99 years old) and Dr Charlene Levitan
DR CHARLENE LEVITAN Centenarians are the fastest growing age worldwide. We can learn about ageing by studying the extremes, especially those who are models of "successful ageing". So how do we live to 100 in good physical and mental health? Approximately 30% of longevity is contributed to be our genes. Parents of centenarians live an average age of 10 years longer than the average life expectancy of the population. Centenarians are four times more likely to have a sibling in their early nineties. The remaining 70% of ingredients relate to the our life style. Montefiore participants in the… Read More

Donating Your Brain to Research

HEIDI DOUGLASS | h.douglass@unsw.edu.au There are currently approximately 320,000 people in Australia with dementia, with that number set to rise to almost one million by 2050, and 115 million globally. These predictions mean that not only do we need a clear plan to make care available for so many people with dementia, but we also need to pursue prevention strategies vigorously. Prevention of dementia depends largely upon research, and beyond the necessities of funding, equipment, and academics with the right skill base to perform the research we need one extra thing: brains. "Even before… Read More