The Organisation of the Elderly Connectome

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Project Main Description: 

Prior investigations of human brain structural networks have primarily focused on healthy young adults and clinical samples. We study the scans of community-dwelling participants aged 70-90 years in order to examine normal age-related changes in the structural organisation of the elderly brain.

Aims: 
  • To examine age-related changes in structural topological organisation of the elderly brain

  • To investigate whether both hemispheric asymmetry and sex differences in structural networks are present in an older population

  • To examine changes in the structural network using functional network measures

Findings: 

Findings from this study were recently published in the journal, Neuroimage. The connectivity data of all cognitively healthy elderly subjects as analysed by Perry et al (http://dx.doi.org/10.1016/j.neuroimage.2015.04.009), collected as part of the Sydney Memory and Ageing Study (MAS), is publicly available here. You will first have to register for access here.

Project Status: 
Current
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